| T or F: there is no cure for iron deficiency anemia |
false; just replace iron |
| This syndrome is associated with dysphagia, anemia (ie iron
deficiency), and increased risk of oral SCCA |
Plummer-Vinson syndrome |
| T or F: dental pts w/ Iron deficiency anemia usually require treatment
modifications. |
false |
| In iron deficiency anemia the lab shows RBC's to be _________ and
contain less ___________ |
small; hemoglobin (microcytic, hypochromic) |
| This type of anemia: depletion of body iron stores, impaired
hemoglobin synthesis |
Iron deficiency anemia |
| The oral findings of this disease are pallor of soft palate, tongue,
sublingual; atrophic tongue, glossodynia (buring sensation) |
Iron deficiency anemia |
| What is the most common cause of anemia? |
Iron deficiency anemia |
| Inc. bleeding, Inc. infections and presence of a neoplastic population
in bone marrow are characteristic of what disease. |
Myelophthisic anemia (aka replacement of marrow by neoplastic cells)
|
| The causes of this disease are: metastatic carcinomas, diseminated
granulomatous diseases, lymphomas, and other rare diseases (like
gaucher's) |
Myelophthisic anemia (aka replacement of marrow by neoplastic cells)
|
| T or F: it is necessary to use Ab prophy for those with aplastic
anemia. |
TRUE |
| What is the only treatment for idiopathic aplastic anemia? |
Bone marrow translplant |
| The symptoms of this anemia are uncontrollable infections (leukopenia)
and a bleeding tendency (thrombocytopenia). |
Aplastic anemia |
| This type of anemia is a generalized bone marrow failure
(pancytopenia) and is usually accompanied by leukopenia and
thrombocytopenia. |
Aplastic anemia |
| The prognosis for idiopathic aplastic anemia compared to secondary
aplastic anemia is __________. |
poorer (a word?) |
| Two types of aplastic anemia. |
Idiopathic, Secondary |
| variation in SIZE of RBC's |
anisocytosis |
| This type of anemia characterized by it's shape (poikilocytosis). |
sickle cell anemia |
| This type of anemia characterized by large, normal color RBC's; could
occur due to Vitamin B12, folic acid deficiency |
macrocytic, normochromic anemia |
| This type of anemia characterized by small pale RBC's; could occur due
to iron deficiency or thalassemaias. |
Microcytic, hypochromic anemia |
| This type of anemia characterized by RBC's with normal color and size;
could occur due to massive blood loss. |
normocytic, normochromic anemia |
| This RBC disease is characterized by somnolence (inadequate brain O2),
fatigue (inadequate O2), and paleness of skin |
anemia |
| A reduction in Hb content in blood |
anemia |
| decrease in all blood elements |
pancytopenia |
| Decrease # of leukocytes |
leukopenia |
| malignant wbc's in lymph nodes or other solid organs or tissues |
lymphoma |
| Malignant disease that involves wbc precursorsin bone marrow and
associated w/ malignant wbc's in peripheral blood. |
leukemia |
| What is a common symptom in all of the following: URTI, infectious
MONO (hopefully paul doesn't have this, cuz I heard you get it from
kissing lots of hot babes), AIDS, cat-scratch disease, TB, metastatic
cancers |
lymphadeopathy |
| Leukocytosis is often accompanied by ___________, a lymph node
enlargement. |
lymphadeopathy |
| What type of leukocytosis occurs in rxn to vial infections &
chronic infections (tb), and some autoimmune disorders |
lymphocytosis |
| what type of leukocytosis occurs in reaction to allergies (hay fever,
asthma) and skin disieases or parasitic infections |
eosinophilic leukocytosis |
| what type of leukocytosis occurs in reaction to an acute bacterial
infection? |
Granulocytosis (neutrophilia) |
| An increase in WBC's above 10,000 per mL is what? |
leukocytosis |
| What types of WBC disorders are there? (4) |
leukopenia, leukocytosis, leukemias and lymphomas, multiple myeloma
|
| A patient with neutropenia has a high risk of __________ infection,
while a patient with lymphopenia has a high risk of _________________
infections |
bacterial; bacterial, viral, fungal, parasitic |
| causes of ________ include: drugs (cancer tx), radiation, aplastic
anemia cyclic neutropenia, metastatic dx to bone marrow |
leukopenia |
| What types of luekopenia are there? |
Neutropenia, lyphopenia, selective lymphopenia |
| what disease? Non-neoplastic, high altitude causes it, anoxia, inc.
erythropoeitin, compensatory increase in rbc |
secondary polycythemia |
| How do you treat polycythemia? |
phlebotomy, anti-leukemia drugs |
| what disease? Hypertension, increased hemoglobin, elevated hematocrit,
red complexion, headaches, splenomegaly, increase incidence towards
clotting |
Polycythemia Vera (aka primary) |
| What is another name for polycythemia? |
erythrocytosis |
| what disease is worldwide, the most common cause of hemolytic anemia?
|
anemia secondary to malaria |
| what disease? Abs recognize self-antigens on rbc's, unknown cause |
autoimmune hemolytic anemia |
| what disease? Drugs attach to rbc surface, act as hapten, produciton
of antibodies, rbc hemolysis |
drug-related hemolytic anemia |
| what disease? Maternal abs cross placenta into fetal circulation, rh
incompatibilities |
erythroblastosis fetalis |
| Immune hemolytic anemias can be caused by what 2 types of antigens?
|
autoantigen (anti-self) or alloantigen (anti-foreign) |
| Anemia due to blood loss will be ______chromic and _______cytic. |
normo; normo |
| What are the diseases associated with decreased hematopoeisis? |
aplastic anemia, replacement of marrow by neoplastic cells, iron
deficiency anemia, vitamin B12 (perniciuos anemia) & folic acid
deficiency, protein deficiency |
| What are the diseases associated with Abnormal hematopoiesis? |
Sickle cell anemia, thalassemia, hereditary spherocytosis |
| what disease: splenomegaly, jaundice, anemia, increased fragiligy of
RBCs in hypotonic solution, gene mutation in structural membrane proteins
(ankrin or spectrin). |
hereditary spherocytosis |
| What is the most common inherited disease of RBC's in caucasians? |
hereditary spherocytosis |
