Clinical study shows dental stem cells regrow bone
NEW YORK--StemSave, a leader in the field of stem cell recovery and cryo-preservation, has lauded research
published in the November issue of the European Cells and Materials Journal that cites reconstruction of the
human mandible bone with autologous dental pulp stem cells.
StemSave commends Italian researchers from the 2nd University of Naples for their work.
This marks the first time dental stem cell research has moved from the laboratory to human clinical trials.
The repair and regeneration of bone is particularly significant for the oral maxillofacial field because the
repair of these bones, which aid in orofacial functions like speech, chewing, swallowing and facial expressions,
are intricate and complex.
According to Dr. David Matzilevich, MD, PhD, science advisor to StemSave, "These clinical studies are so
significant because autologous dental stem cells were expanded in vitro and for the purpose of oro-maxillofacial
bone repair. These cells also facilitated the graft, eliminating immunologic complications such as rejection
or excessive inflammation. This is compelling because it creates an environment which proves to be more favorable
and successful for new mandibular bone to grow.
"This approach," continued Dr. Matzilevich, "also appears superior to current methodologies utilizing cadaverous
tissue or grafting tissue from another part of the body. I am very excited that dental stem cells have emerged
as critical players in tissue engineering and regenerative medicine now that they have been proven to
differentiate into multiple lineages."
Added Art Greco, CEO of StemSave: "This breakthrough clinical study, which uses the patient's own stem cells
harvested from their teeth to repair bone, is the first of what we believe will be an expanding number of
applications to treat a broad array of disease, trauma and injury. And because dental stem cells are easy
to recover as part of routine dental procedures, this represents the first of many upcoming uses in the field
of personal and regenerative medicine and supports the wisdom of banking your own stem cells from your teeth."
Infective Endocarditis
For decades, the American Heart Association (AHA) recommended that patients with certain heart conditions take
antibiotics shortly before dental treatment. This was done with the belief that antibiotics would prevent infective
endocarditis (IE), previously referred to as bacterial endocarditis. The AHA’s latest guidelines were published in
its scientific journal, Circulation, in April 2007 and there is good news: the AHA recommends that most of these
patients no longer need short-term antibiotics as a preventive measure before their dental treatment -
Click here for more details
Jones on Dental Technology: Genetics - A new way to make teeth in the lab
Volan Design wins 2001 Medical Design Excellence Award for Waterpik Flosser
Dental problems go unresolved in many HIV patients
Undergraduate conducts high-tech tests on dental enamel
Early Dental and Vision Care: A crucial component of children's health
Risk Management: Curing the risk of sick building syndrome
Jones on Dental Technology: Going through a midline crisis
Federal Measure Preventing Needlestick Injuries Takes Effect
AACD Announces Its New Dental Protocol For Accreditation
Chronic Periodontal Disease Could Lead to Diabetes
Sweet Tooth Gene Identified
Preventing Needlestick Injuries
A Simple genetic test to identify oral cancer
Canadian study: Stop fluoridation in water
New Butler GUM(R) Toothbrush Gives Germs the Brush Off
1) Jones on Dental Technology: Genetics - A new way to make teeth in the lab Trying to
create a natural-looking tooth is the goal of most dental technicians. But, what many
dental technicians don't know is that natural teeth are already being creating
in a lab in the United States ... a scientific lab, that is.
For more, visit here...
2) Volan Design wins 2001 Medical Design Excellence Award for Waterpik Flosser
- Volan Design and Waterpik Technologies, Inc. won a top award for the product design
of the Waterpik Flosser in the category of dental instruments, equipment, and supplies.
For more, visit here...
3) Dental problems go unresolved in many HIV patients
Oral infections, mouth ulcers, and other severe dental conditions associated with HIV
infections go untreated more than twice as often as other health problems related to
the disease. For more, visit here...
4) Undergraduate conducts high-tech tests on dental enamel
A undergraduate biomedical engineering major at The Johns Hopkins University is
conducting ground-breaking research to help scientists find out how human tooth enamel
is affected by acids that reach the mouth through acid reflux. For more, visit here...
5) Early Dental and Vision Care: A crucial component of children's health
PacifiCare Dental & Vision Administrators is supporting educational programs that keep
dentists abreast of methodologies to better serve children in dentistry, along with
community-based public health efforts to promote fluoridation of water supplies.
For more, visit here...
6) Risk Management: Curing the risk of sick building syndrome
Is your dental office making you or your staff ill? It could be sick building syndrome.
Sick building syndrome occurs when building occupants suffer acute health effects
associated with time spent indoors, but with no specific identifiable illness or cause.
For more, visit here...
7) Jones on Dental Technology: Going through a midline crisis
Dentists often find it difficult to communicate the angle of a patient's midline and incisal plane
to their labs, especially when the patient's skeletal features are asymmetrical.
The problem is so common that it has led some dentists and labs to search for a solution
to the midline crisis. >For more, visit here...
8) Federal Measure Preventing Needlestick Injuries Takes Effect
A federal measure takes effect that will potentially save the lives of thousands of nurses
and other front-line health care workers each year by protecting them from dangerous
needlestick injuries.
9) AACD Announces Its New Dental Protocol For Accreditation
The American Academy of Cosmetic Dentistry (AACD) is proud to announce the new dental protocol
for Accreditation on Thursday May 24, 2001 during the AACD's 17th Annual Scientific Session in
Boston, Mass.
10) Chronic Periodontal Disease Could Lead to Diabetes
Chronic periodontal disease may contribute to diabetes. While it has been established that
people with diabetes are more prone to developing periodontal disease, new research is
suggesting that periodontal disease may, in turn, be a risk factor for diabetes.
11) Sweet Tooth Gene Identified
Preference for sweetness over bitterness is not just a matter of taste. Over the past few
years, receptors and signaling proteins responsible for bitter taste have been identified but,
until now, the identity of the 'sweet' taste receptor has been a mystery.
12) Preventing Needlestick Injuries
How can I work in my institution to prevent needlestick injuries?" someone asked
herself this question five years ago after learning that a needlestick injury had
infected her with the human immuno- deficiency virus (HIV). She has since launched
the National Campaign for Healthcare Worker Safety, in order to educate nurses and
facilities on needlestick injuries, and to urge hospitals to implement safer devices.
Like this, you may be among the thousands of health care workers who annually receive
a needlestick contaminated with HIV. According to the a recent report, more than one
million needlestick injuries to health care workers occur every year. .....
13) A simple genetic test may help doctors accurately predict whether people with common white
patches inside their mouths are likely to develop deadly oral cancer. The technique developed
at the University of Oslo could help physicians assess patients with the patches, called oral
leukoplakia, so they can be treated early if cancer appears likely.
14) Canadian study: Stop fluoridation in water
Big news out of Canada: a new report from the Canadian government claims that fluoridation
in water probably does more harm than good. Report author Dr. David Locker, a professor of
dentistry at the University of Toronto, suggests that the best solution is to cease fluoridation.
15) New Butler GUM(R) Toothbrush Gives Germs the Brush Off
CHICAGO, May 1 /PRNewswire/ -- Every day millions of germs make the average toothbrush their
home. Now there's a toothbrush that gives bacteria an eviction notice. Butler GUM® announces
the first-ever antibacterial bristle toothbrush with replaceable heads